Platelet Rich Plasma PRP

Platelet Rich Plasma PRP

Everything You Need To Know About PRP or Platelet Rich Plasma

What is Platelet Rich Plasma?

Platelet Rich Plasma(PRP) is an autologous(from your own body) procedure, concentrating a high dose of platelets in a small amount of plasma.  This is done by drawing a small amount of blood and centrifuging to separate the plasma, platelets, monocytes and lymphocytes from the red blood cells.  A buffy coat of platelets will form in between the plasma and the red blood cells. The plasma and buffy coat are drawn off and used. The buffy coat contains a high concentration of platelets and monocytes that will speed up the healing process.

How Does PRP Work?

Platelet Rich Plasma is concentrated with growth factors.  These growth factors are healing agents within the body. When a micro injury occurs, the growth factors signal to the other healthy cells in the body to start healing and help produce healthy tissue.  When platelet rich plasma comes in contact with the collagen layer of the skin, it activates, and the healing process begins. Creating new collagen, vascularization, skin cells, hair follicles. Utilizing your own body’s PRP, you can fight the aging process.

 

  • EGF (Epidermal Growth Factor)-Promotion of epithelial cell growth, blood vessel formation, wound healing, skin growth
  • FGF (Fibroblast Growth Factor)-Tissue Repair, Cell Growth, Collagen Production
  • PDGF (Platelet Derived Growth Factor)-Plays a significant role in blood vessel formation, cell growth, proliferation of mesenchymal stem cells
  • VEGF (Vascular Endothelial Growth Factor)-Regeneration of cells lining the blood vessels and lymphatic system
  • IGF (Insulin-like growth factor)-Stimulates growth hormone, produced in the hair follicle and promotes growth
  • KGF (keratinocyte growth factor)-These cells cover the epithelial cells(epidermis) during wound healing phase

 

Monocytes play a role in platelet function and EmCyte is the only system on the market to get high enough concentrations of Monocytes.  Monocytes are responsible for cleaning the area of injury and have potent tissue regeneration capabilities.

Is all PRP the same?  

No.  Tube Systems(gel separator) do not get high enough concentrations and some are not FDA cleared for reapplication to the body. Test Tube systems only produce PPP(platelet poor plasma).   A vial that produces a buffy coat of platelets will yield the best PRP for all applications. Know what you are injecting. A proper PRP system will produce a viable number of platelets(>5 billion platelets).

Why the PRP kit matters?

In order for PRP to be effective the kit must produce a high enough concentration of platelets to elicit a response also known as clinical PRP(total amount of deliverable platelets, usually >5 billion platelets)  The kit must be FDA cleared, sterile and pyrogen free. The kit must be a closed system to avoid contamination. The PRP kit must be able to capture all of the healing and regenerating properties of the blood. This can only be accomplished using a vial that will accurately separate out all the components(Plasma, Platelets, Monocytes, Lymphocytes, Neutrophils, Erythrocytes).  Emcyte has the ONLY system on the market that captures a high enough concentration of MONOCYTES which are key in supporting platelet function. (Insert slide with PRP vial and separation with definitions) The anti-coagulant used in the blood draw also matters. Most anti-coagulants contain a high level of glucose which can destroy platelets. Sodium Citrate(used in the EmCyte system) has a low glucose level, therefore will have a higher proliferation of cells.

What skin conditions will PRP help with?

PRP is trending in aesthetics due to its promising results.  The most common PRP procedure is microneedling with PRP. The microneedling device creates a tiny injury to the skin igniting the healing process.  When PRP is added to the micro channels, the growth factors in the PRP signal to other healthy cells in your body to come to the area of injury and help create new healthy skin, blood vessels and collagen.  The same response occurs when PRP is injected to the scalp for Hair Restoration. The Growth Factors tell the hair follicle to “wake up” and begin growing stronger, thicker follicles. Sexual Wellness is a more recent application added to the PRP portfolio, but elicits the same healing response when injected.  PRP can help with fine lines, dark spots, rosacea, acne, acne scarring, stretch marks, skin tone and texture, hair restoration, sexual wellness.

How often should PRP treatments be given?

PRP treatments should be seen as preventative treatments as well as corrective treatments.  PRP treatments help build new collagen and blood vessels, which aid in the anti-aging process.  PRP treatments should be a part of your quarterly/semiannual aesthetic maintenance. PRP treatments enhance your aesthetic over time and are not an immediate fix.  PRP treatments are adjunctive to any other aesthetic treatment (filler, botulinum toxin, laser, peels, daily skin care). Treatment protocols vary between applications.  Most treatments require a 3-4 injection or needling series to see sustainable results. Treatments are usually spaced about 4-6 weeks a part. Hair grows in a 4 phase process. The anagen is the growing phase and usually lasts 2-7 years.  The length of the anagen phase also determines the length of the hair and is also determined by your genetics.  The Catagen Phase is the transitional stage that usually lasts about 2 weeks.  The Catagen Phase is the renewal phase where the hair follicle shrinks and is cut off from blood supply. This Phase is signaled by the end of melanin production in the hair bulb and death of follicular cells.   The Telogen is the resting phase which lasts around three months. Around 10-15 percent of hairs are in this phase. In this phase the epidermal cells lining the follicle channel continue to grow as normal and may accumulate around the base of the hair, temporarily anchoring it in place and preserving the hair for its natural purpose. The Exogen Phase is part of the resting phase where the old hair sheds and a new hair continues to grow. Approximately 50 to 150 hairs can fall out daily, this is considered to be normal hair shedding.  PRP concentrates your own growth factors to stimulate your hair follicles and keep the follicles active longer.

What is the recovery time with a PRP treatment?

PRP is one of the most popular treatments for the results alone but a huge factor pertaining to its success is how little the recovery time is.  Most patients will be able to resume normal activities same day. Facial Rejuvenation results in slight swelling and a look of a sunburn. Hair Restoration procedures result in slight swelling and redness which may be noticeable on men.  Women will have damp hair from the PRP. Due to the lack of space in the scalp, hair treatments may leave a slight pressure in the scalp, which subsides within 24 hours. All patients can resume regular hair and skin care within 48 hours.

Why add PRP treatments to your practice?

PRP continues to be one of the top treatments requested by patients.  PRP is an affordable treatment option for all patients. All skin types can benefit from a PRP treatment.   Minimally invasive, more natural treatment options are what patients want. Patients want little to no downtime but want results and that is what PRP offers.  PRP opens the door to more patient types because there are so many different treatment options and more research is being done to increase these options. PRP treatments are not a 1 and done.  PRP takes affect over time and must be performed on a quarterly/semi-annual basis to see results and maintain these results. A patient that invests in PRP treatments, is investing in his or hers over all skin and hair health for a lifetime.  Investing in a PRP system, is investing in the future of your practice.

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